Acute Pain Management by Sinatra R.S., Ginsberg B., Viscusi E.

By Sinatra R.S., Ginsberg B., Viscusi E.

This textbook presents an summary of discomfort administration precious to experts in addition to non-specialists, surgeons, and nursing employees.

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Beilin B, Shavit Y, Trabekin E, et al. The effects of postoperative pain management on immune response to surgery. Anesth Analges. 2003;97(3):822–827. 45. Winter J, Bevan S, Campbell EA. Capsaicin and pain mechanisms. Br J Anaesth. 1995;75(2):157–168. 46. Djouhri L, Koutsikou S, Fang X, McMullan S, Lawson SN. Spontaneous pain, both neuropathic and inflammatory, is related to frequency of spontaneous firing in intact C-fiber nociceptors. J Neurosci. 2006;26(4):1281–1292. 47. Hogan QH, Abram SE. Neural blockade for diagnosis and prognosis: a review.

These cells also make important connections within the spinal cord. Synapses made with ventral horn motor neurons are responsible for reflexive musculoskeletal withdrawal responses observed with physiologic pain and important for minimizing tissue damage during traumatic injury. Increased excitability of motor neurons is also responsible for segmental ipsilateral and contralateral increases in skeletal muscle tone termed hyperreflexia or splinting. Telologically, muscle splinting and hyperreflexia have evolved to inhibit movement and encourage wound healing; however, these same responses can also impair pulmonary function and rehabilitation following surgical and traumatic injuries.

Subthreshold components of the cutaneous mechanoreceptive fields of dorsal horn neurons in the rat lumbar spinal cord. J Neurophysiol. 1989;62(4):907–916. 4. Andersson GB. Epidemiological features of chronic low-back pain. Lancet. 1999;354(9178):581–585. 5. Smith BH, Elliott AM, Chambers WA, Smith WC, Hannaford PC, Penny K. The impact of chronic pain in the community. Fam Pract. 2001;18(3):292–299. 6. Mannion RJ, Costigan M, Decosterd I, et al. Neurotrophins: peripherally and centrally acting modulators of tactile stimulusinduced inflammatory pain hypersensitivity.

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